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Extending the half-life has become a key issue in GLP-1-related studies

A broad review of real-world evidence found frequent gastrointestinal effects consistent with the trials, without clear increases in rates of several severe outcomes that had been raised as concerns

10.3390/ijms20143532 6 Amgen (2024)

Research models suggest it can support GH release without the broader hormonal noise associated with less selective compounds

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Women prescribed GLP-1 medications for licensed indications who also experience menopausal symptoms should discuss their full symptom profile with their healthcare provider